公开(公告)号：US20210139992A1

公开(公告)日：2021-05-13

申请号：US16492524

申请日：2018-03-09

Applicant: BAYLOR RESEARCH INSTITUTE

Inventor： Ajay GOEL ,  Daisuke IZUMI

IPC: C12Q1/6886

Abstract: Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Aspects of the disclosure relate to methods for selecting optimal therapy for a patient from several alternative treatment options. A major clinical challenge in cancer treatment is to identify the subset of patients who will benefit from a therapeutic regimen, both in metastatic and adjuvant settings. The number of anti-cancer drugs and multi-drug combinations has increased substantially in the past decade, however, treatments continue to be applied empirically using a trial-and-error approach. Here methods and compositions are provided to determine the optimal treatment option for gastric cancer patients.