公开(公告)号：US10570398B2

公开(公告)日：2020-02-25

申请号：US15559362

申请日：2016-03-17

Applicant: BAYLOR RESEARCH INSTITUTE

Inventor： Ajay Goel ,  Kunitoshi Shigeyasu

IPC: A61K48/00 ,  C07H21/02 ,  C07H21/04 ,  C12N15/113 ,  C12Q1/6886 ,  G01N33/574 ,  A61P35/04 ,  A61P35/00 ,  C07K16/28 ,  C07K16/32

Abstract: Certain embodiments provide methods and compositions related to clinical management of cancer patients based on the expression level of TMCO3. Further embodiments involve methods and compositions related to treatment of cancer patients or patients determined to have an increased TMCO3 level relative to a control or a reference level that is normal or indicating favorable prognosis.