公开(公告)号：US20210308242A1

公开(公告)日：2021-10-07

申请号：US17301704

申请日：2021-04-12

Applicant: BAYLOR RESEARCH INSTITUTE

Inventor： Gerard ZURAWSKI ,  Jacques F. Banchereau ,  Anne-Laure FLAMAR ,  Peter KLUCAR ,  Keiko AKAGAWA ,  Sandra ZURAWSKI ,  SangKon OH

IPC: A61K39/00 ,  C07K16/28 ,  C07K14/435

Abstract: The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.