公开(公告)号：US20130231462A1

公开(公告)日：2013-09-05

申请号：US13776403

申请日：2013-02-25

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： Steve Roth ,  William Strong

IPC: C07K16/42

CPC classification number: C07K16/42 ,  C07K2317/31 ,  C07K2317/32

Abstract: Provided are methods and compositions for immunoassays with improved sensitivity and specificity. The presently disclosed anti-immune complex antibodies stabilize the interaction between a primary and secondary antibody, thereby allowing for more stringent wash conditions, less background, and stronger signal.

Abstract translation: 提供了具有改善的灵敏度和特异性的免疫测定法的方法和组合物。 目前公开的抗免疫复合物抗体稳定了一级和二级抗体之间的相互作用，从而允许更严格的洗涤条件，更少的背景和更强的信号。