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公开(公告)号：US09394277B2
公开(公告)日：2016-07-19
申请号：US14406315
申请日：2013-06-07
Applicant: BIOGEN IDEC MA INC. , SUNESIS PHARMACEUTICALS, INC.
Inventor： Brian T. Hopkins , Patrick Conlon , Timothy R. Chan , Tracy J. Jenkins , Xiongwei Cai , Michael Humora , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: A61K31/506 , C07D401/14
CPC classification number: C07D401/14
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
Abstract translation: 本发明提供了可用作Bruton酪氨酸激酶抑制剂的化合物及其组合物，并且其表现出所需特性。
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公开(公告)号：US20150158843A1
公开(公告)日：2015-06-11
申请号：US14406315
申请日：2013-06-07
Applicant: BIOGEN IDEC MA INC. , SUNESIS PHARMACEUTICALS, INC.
Inventor： Brian T. Hopkins , Patrick Conlon , Timothy R. Chan , Tracy J. Jenkins , Xiongwei Cai , Michael Humora , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: C07D401/14
CPC classification number: C07D401/14
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
Abstract translation: 本发明提供了可用作Bruton酪氨酸激酶抑制剂的化合物及其组合物，并且其表现出所需特性。
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公开(公告)号：US09353087B2
公开(公告)日：2016-05-31
申请号：US14406081
申请日：2013-06-07
Applicant: Biogen Idec MA Inc. , Sunesis Pharmaceuticals, Inc.
Inventor： Brian T. Hopkins , Xiongwei Cai , Timothy R. Chan , Patrick Conlon , Michael Humora , Tracy J. Jenkins , Michael J. Macphee , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: A61K31/506 , C07D401/14
CPC classification number: C07D401/14 , C07B2200/13 , C07D207/16 , C07D207/28 , C07D211/56 , C07D401/04
Abstract: The present invention provides a compound, solid forms, and compositions thereof, which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same. The present invention also provides methods of making provided compound and solid forms.
Abstract translation: 本发明提供了一种化合物，固体形式及其组合物，其可用作Bruton酪氨酸激酶的抑制剂，并且其表现出对其的期望特性。 本发明还提供了制备所提供的化合物和固体形式的方法。
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公开(公告)号：US20150126528A1
公开(公告)日：2015-05-07
申请号：US14406081
申请日：2013-06-07
Applicant: Biogen Idec MA Inc. , Sunesis Pharmaceuticals, Inc.
Inventor： Brian T. Hopkins , Xiongwei Cai , Timothy R. Chan , Patrick Conlon , Michael Humora , Tracy J. Jenkins , Michael J. Macphee , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: C07D401/14
CPC classification number: C07D401/14 , C07B2200/13 , C07D207/16 , C07D207/28 , C07D211/56 , C07D401/04
Abstract: The present invention provides a compound, solid forms, and compositions thereof, which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same. The present invention also provides methods of making provided compound and solid forms.
Abstract translation: 本发明提供了一种化合物，固体形式及其组合物，其可用作Bruton酪氨酸激酶的抑制剂，并且其表现出对其的期望特性。 本发明还提供了制备所提供的化合物和固体形式的方法。
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Patent Agency Ranking
公开(公告)号：US20180291001A1
公开(公告)日：2018-10-11
申请号：US15875629
申请日：2018-01-19
Applicant: BIOGEN MA INC. , Sunesis Pharmaceuticals, Inc.
Inventor： Brian T. Hopkins , Xiongwei Cai , Timothy R. Chan , Patrick Conlon , Michael Humora , Tracy J. Jenkins , J. Michael Macphee , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: C07D401/14 , C07D207/16 , C07D211/56 , C07D207/28 , C07D401/04
CPC classification number: C07D401/14 , C07B2200/13 , C07D207/16 , C07D207/28 , C07D211/56 , C07D401/04
Abstract: The present invention provides a compound, solid forms, and compositions thereof, which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same. The present invention also provides methods of making provided compound and solid forms.
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公开(公告)号：US10189817B2
公开(公告)日：2019-01-29
申请号：US15875629
申请日：2018-01-19
Applicant: BIOGEN MA INC. , Sunesis Pharmaceuticals, Inc.
Inventor： Brian T. Hopkins , Xiongwei Cai , Timothy R. Chan , Patrick Conlon , Michael Humora , Tracy J. Jenkins , J. Michael Macphee , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: C07D401/14 , C07D401/04 , C07D211/56 , C07D207/28 , C07D207/16
Abstract: The present invention provides a compound, solid forms, and compositions thereof, which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same. The present invention also provides methods of making provided compound and solid forms.
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公开(公告)号：US09944622B2
公开(公告)日：2018-04-17
申请号：US15196389
申请日：2016-06-29
Applicant: Biogen MA Inc. , Sunesis Pharmaceuticals, Inc.
Inventor： Brian T. Hopkins , Timothy R. Chan , Tracy J. Jenkins , Patrick Conlon , Xiongwei Cai , Michael Humora , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: A61K31/506 , C07D401/14
CPC classification number: C07D401/14
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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公开(公告)号：US20170114039A1
公开(公告)日：2017-04-27
申请号：US15167508
申请日：2016-05-27
Applicant: Biogen MA Inc. , Sunesis Pharmaceuticals, Inc.
Inventor： Brian T. Hopkins , Xiongwei Cai , Timothy R. Chan , Patrick Conlon , Michael Humora , Tracy J. Jenkins , J. Michael Macphee , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: C07D401/14 , C07D401/04 , C07D207/16 , C07D211/56 , C07D207/28
CPC classification number: C07D401/14 , C07B2200/13 , C07D207/16 , C07D207/28 , C07D211/56 , C07D401/04
Abstract: The present invention provides a compound, solid forms, and compositions thereof, which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same. The present invention also provides methods of making provided compound and solid forms.
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公开(公告)号：US20160304494A1
公开(公告)日：2016-10-20
申请号：US15196389
申请日：2016-06-29
Applicant: Biogen MA Inc. , Sunesis Pharmaceuticals, Inc.
Inventor： Brian T. Hopkins , Timothy R. Chan , Tracy J. Jenkins , Patrick Conlon , Xiongwei Cai , Michael Humora , Xianglin Shi , Ross A. Miller , Andrew Thompson
IPC: C07D401/14
CPC classification number: C07D401/14
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
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