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1.发明授权公开(公告)号：US11345904B2
公开(公告)日：2022-05-31
申请号：US16078546
申请日：2017-02-24
Applicant: BIOMARIN PHARMACEUTICAL INC.
Inventor： Saeed Moshashaee , Jason K. Pinkstaff , Adam Shaywitz , Natalie Ciaccio
Abstract: The present disclosure relates in general to therapeutic lysosomal enzyme fusion proteins useful for treating lysosomal storage diseases, liquid formulations comprising such fusion proteins and associated methods useful for treating lysosomal storage diseases in mammals.
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公开(公告)号：US12214015B2
公开(公告)日：2025-02-04
申请号：US17541992
申请日：2021-12-03
Applicant: BIOMARIN PHARMACEUTICAL INC.
Inventor： Charles A. O'Neill , Todd M. Oppeneer , Jason K. Pinkstaff
IPC: A61K38/22 , A61K9/19 , A61K31/573 , A61K31/728 , A61P19/02 , C07K14/58
Abstract: The disclosure relates to the use of variants of C-type natriuretic peptide (CNP) to treat osteoarthritis, to ameliorate one or more symptoms of osteoarthritis, and to treat disorders having an osteoarthritis component.
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公开(公告)号：US20220160836A1
公开(公告)日：2022-05-26
申请号：US17541992
申请日：2021-12-03
Applicant: BIOMARIN PHARMACEUTICAL INC.
Inventor： Charles A. O'Neill , Todd M. Oppeneer , Jason K. Pinkstaff
IPC: A61K38/22 , C07K14/58 , A61P19/02 , A61K9/19 , A61K31/573 , A61K31/728
Abstract: The disclosure relates to the use of variants of C-type natriuretic peptide (CNP) to treat osteoarthritis, to ameliorate one or more symptoms of osteoarthritis, and to treat disorders having an osteoarthritis component.
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公开(公告)号：US11202819B2
公开(公告)日：2021-12-21
申请号：US15779049
申请日：2016-12-08
Applicant: BIOMARIN PHARMACEUTICAL INC.
Inventor： Charles A. O'Neill , Todd M. Oppeneer , Jason K. Pinkstaff
IPC: A61K38/22 , C07K14/58 , A61P19/02 , A61K9/19 , A61K31/573 , A61K31/728
Abstract: The disclosure relates to the use of variants of C-type natriuretic peptide (CNP) to treat osteoarthritis, to ameliorate one or more symptoms of osteoarthritis, and to treat disorders having an osteoarthritis component.
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