公开(公告)号：US20240415828A1

公开(公告)日：2024-12-19

申请号：US18704537

申请日：2022-11-09

Applicant: BIONTECH SE

Inventor： Ugur SAHIN ,  Hariz Iskandar Bin HASSAN ,  Stefan STROBL ,  Roman RÖSEMANN

IPC: A61K31/4745 ,  A61K9/00 ,  A61K31/555 ,  A61K31/7048 ,  A61K39/00 ,  A61P35/00 ,  C07D471/04 ,  C07K16/28

Abstract: The present disclosure relates to the specific TLR7 agonist BNT411, such as compositions and kits comprising BNT411, and the use of BNT411 as immunotherapeutic agent in monotherapy and combination therapy to reduce or prevent progression of a tumor, in particular a solid tumor, or treating cancer, in particular a solid cancer.