公开(公告)号：US20210238259A1

公开(公告)日：2021-08-05

申请号：US16478747

申请日：2018-01-31

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Arjan VAN DER FLIER ,  Zhiqian LIU ,  David R. LIGHT ,  Ekta Seth CHHABRA ,  Tongyao LIU ,  Robert T. PETERS ,  John KULMAN ,  Ayman ISMAIL

IPC: C07K14/745 ,  C12N9/64

Abstract: The present disclosure provides Factor IX (FIX) fusion proteins comprising at least one heterologous moiety, such as an XTEN. The present disclosure further discloses methods of making and using the FIX fusion proteins.

公开(公告)号：US20210032616A1

公开(公告)日：2021-02-04

申请号：US16920970

申请日：2020-07-06

Applicant: Bioverativ Therapeutics Inc.

Inventor： Zhiqian LIU ,  Arjan VAN DER FLIER ,  David R. LIGHT ,  Ekta Seth CHHABRA ,  Tongyao LIU ,  Robert T. PETERS ,  John KULMAN ,  Ayman ISMAIL

IPC: C12N9/64 ,  A61K9/00 ,  A61P7/04 ,  C07K14/00

Abstract: The present invention provides Factor IX (FIX) fusion proteins comprising at least one heterologous moiety, such as an XTEN. The present invention further discloses methods of making and using the FIX fusion proteins.