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公开(公告)号：US20230091932A1
公开(公告)日：2023-03-23
申请号：US17821356
申请日：2022-08-22
Applicant: BIOVERATIV THERAPEUTICS INC.
Inventor： Ajay Maghodia , Christian Mueller , Tongyao Liu
IPC: C12N15/113 , C12N15/86 , C07K14/755 , A61K31/713
Abstract: The present disclosure provides nucleic acid molecules comprising a first inverted terminal repeat (ITR), a second ITR, and a genetic cassette encoding a target sequence. In some embodiments, the first ITR and/or the second ITR is an ITR of human bocavirus. Also disclosed are methods of using the nucleic acid molecules in gene therapy applications.
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