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公开(公告)号:US20220233650A1
公开(公告)日:2022-07-28
申请号:US17618808
申请日:2020-06-18
Applicant: BIOVERATIV THERAPEUTICS INC.
Inventor: Susu DUAN , Katalin KIS-TOTH , Gaurav Manohar RAJANI , Joe SALAS
Abstract: Disclosed herein are methods of treating subjects with hemophilia and low bone mineral density (BMD) with a chimeric protein comprising a coagulation factor and a Fc domain. In certain embodiments, the chimeric protein is rFVIIIFc. In certain embodiments, a subject to be treated has hemophilia A.