公开(公告)号：US12257288B2

公开(公告)日：2025-03-25

申请号：US16464105

申请日：2017-12-01

Applicant: BIOVERATIV THERAPEUTICS INC. ,  SWEDISH ORPHAN BIOVITRUM AB

Inventor： Jennifer Dumont ,  Nisha Jain ,  Stefan Lethagen

IPC: A61K38/37 ,  A61K38/48 ,  A61P7/04

Abstract: The present disclosure provides methods inducing immune tolerance in a human, comprising administering to the human an effective amount of a composition or a chimeric protein comprising a clotting factor and an Fc region.

公开(公告)号：US12161696B2

公开(公告)日：2024-12-10

申请号：US16463748

申请日：2017-12-01

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Jennifer Dumont ,  Nisha Jain ,  Desilu Glazebrook

IPC: A61K38/37 ,  A61K38/48 ,  A61P7/04 ,  A61P19/02

Abstract: The present disclosure provides methods treating reversible hemophilic arthropathy of a joint in a human having hemophilia comprising administering to the human an effective amount of a chimeric protein or composition comprising a clotting factor and an Fc region.