公开(公告)号：US20180002684A1

公开(公告)日：2018-01-04

申请号：US15619196

申请日：2017-06-09

Applicant: Bioverativ Therapeutics Inc.

Inventor： Glenn PIERCE ,  Samantha TRUEX ,  Robert T. PETERS ,  Haiyan JIANG

IPC: C12N9/64 ,  C07K16/36 ,  C07K14/745 ,  A61K38/00

CPC classification number: C12N9/644 ,  A61K38/00 ,  C07K14/745 ,  C07K16/36 ,  C07K2317/76 ,  C07K2319/30 ,  C12Y304/21022

Abstract: The present invention provides methods of administering long-acting Factor IX; methods of administering long-acting, chimeric and hybrid polypeptides comprising Factor IX; and methods of producing such chimeric and hybrid polypeptides using cells.

公开(公告)号：US20210008178A1

公开(公告)日：2021-01-14

申请号：US16907985

申请日：2020-06-22

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Glenn PIERCE ,  Samantha TRUEX ,  Robert T. PETERS ,  Haiyan JIANG

IPC: A61K38/48 ,  A61K47/64 ,  A61K39/395 ,  C12N9/96 ,  A61K38/38 ,  C07K16/18 ,  C12N9/64 ,  C07K14/76 ,  A61K9/00 ,  A61P7/04

Abstract: The present invention provides methods of administering Factor IX; methods of administering chimeric and hybrid polypeptides comprising Factor IX; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.

公开(公告)号：US20220064622A1

公开(公告)日：2022-03-03

申请号：US17378200

申请日：2021-07-16

Applicant: Bioverativ Therapeutics Inc.

Inventor： Glenn PIERCE ,  Samantha TRUEX ,  Robert T. PETERS ,  Haiyan JIANG ,  Mark BRADER

IPC: C12N9/64 ,  C07K14/745 ,  C07K16/36

Abstract: The present invention provides methods of administering long-acting Factor IX; methods of administering long-acting, chimeric and hybrid polypeptides comprising Factor IX; and methods of producing such chimeric and hybrid polypeptides using cells.

公开(公告)号：US20210023185A1

公开(公告)日：2021-01-28

申请号：US17032354

申请日：2020-09-25

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Glenn PIERCE ,  Samantha TRUEX ,  Robert T. PETERS ,  Haiyan JIANG

IPC: A61K38/48 ,  A61P7/04 ,  A61K47/64 ,  A61K38/38 ,  A61K39/395 ,  C07K16/18 ,  C12N9/64 ,  C07K14/76 ,  A61K9/00 ,  C12N9/96

Abstract: The present invention provides methods of administering Factor IX; methods of administering chimeric and hybrid polypeptides comprising Factor IX; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.