公开(公告)号：US3917686A

公开(公告)日：1975-11-04

申请号：US51224774

申请日：1974-10-07

Applicant: BJORKSTEN RESEARCH LAB INC

Inventor： BRUSON HERMAN ALEXANDER

IPC: C07C51/08 ,  C07C59/265 ,  C07C59/16

CPC classification number: C07C255/00 ,  C07C51/08 ,  C07C59/265

Abstract: Citric acid is prepared in a process consisting essentially of the following steps:

The first step is improved by carrying out the reaction in the presence of a solvent selected from high boiling esters of polybasic acids, which remain liquid at the reaction temperature of -10 to +25*C.

Abstract translation: 柠檬酸以基本上由以下步骤组成的方法制备：1. COCl 2 + 2 CO = CH 2 + 2 C 2 H 5 OH-> CO（CH 2 COOC 2 H 5）2 HOCH 2 COOC 2 H 5 2.CO（CH 2 COOC 2 H 5）2 + HCN->角度C角NCCH 2 COOC 2 H 5 HOCH 2 COOC 2 H 5 4 H 2 O 3.角度角 - > NCCH 2 COOC 2 H 5 - > HO.C 3 H 4（COOH）3 + NH 4 Cl + 2 C 2 H 5 OH通过在选自多元酸的高沸点酯的溶剂的存在下进行反应来改善第一步， 在-10至+25℃的反应温度下保持液体。