公开(公告)号：US3846440A

公开(公告)日：1974-11-05

申请号：US6148770

申请日：1970-08-05

申请人： BLIND A ,  BOESCH R ,  CASSAL J

发明人： CASSAL J ,  BOESCH R ,  BLIND A

IPC分类号： C07D271/10 ,  C07D271/113 ,  C07D85/54

CPC分类号： C07D271/113

摘要： 3-(2,4-Dichlorophenyl)-5-t-butyl-1,3,4-oxadiazol-2-ones of the formula: IN WHICH R represents a hydrogen atom or an alkoxy group containing one to four carbon atoms, which possess herbicidal properties, are prepared by a new process involving reaction of a halogenonitrobenzene of the formula: IN WHICH Y represents a halogen atom and R is as defined, with an alkali metal salt of 5-t-butyl-1,3,4-oxadiazol-2-one, reduction of the nitro group in the resulting 3-(2-chloro-4nitrophenyl)-5-t-butyl-1,3,4-oxadiazol-2-one, which may carry an alkoxy substituent R in the 5-position of the benzene ring, to a primary amino group, and replacement of the amino group in the resulting 3-(2-chloro-4-aminophenyl)-5-t-butyl-1,3,4-oxadiazol-2one by a chlorine atom by reaction of cuprous chloride with a diazonium salt derived from the amino compound. The process avoids the use of phosgene - an awkward reagent hitherto employed in the production of the 3-(2,4-dichlorophenyl)-5-t-butyl-1,3,4oxadiazol-2-ones.

摘要翻译： 3-（2,4-二氯苯基）-5-叔丁基-1,3,4-恶二唑-2-酮，其具有下式：