公开(公告)号：US11103579B2

公开(公告)日：2021-08-31

申请号：US15993687

申请日：2018-05-31

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Bryan Barnhart ,  Maria N. Jure-Kunkel

IPC: A61K39/395 ,  C07K16/28 ,  A61K39/00

Abstract: Provided are methods and compositions for treating cancer using an effective amount of a PD-1 antagonist in combination with a DR4 or DR5 agonist.

公开(公告)号：US20180360962A1

公开(公告)日：2018-12-20

申请号：US15993687

申请日：2018-05-31

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Bryan Barnhart ,  Maria N. Jure-Kunkel

IPC: A61K39/395 ,  C07K16/28

Abstract: Provided are methods and compositions for treating cancer using an effective amount of a PD-1 antagonist (e.g., an antibody) in combination with a DR4 or DR5 agonist (e.g., an antibody).