公开(公告)号：US20230322695A1

公开(公告)日：2023-10-12

申请号：US18161184

申请日：2023-01-30

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Haibo Liu ,  Laura Akullian D′Agostino ,  Shoshana L. Posy ,  Annapurna Pendri ,  Swanee E. Jacutin-Porte

IPC: C07D285/06 ,  A61K45/06 ,  A61P35/00 ,  C07D417/12 ,  C07D417/10

CPC classification number: C07D285/06 ,  A61K45/06 ,  A61P35/00 ,  C07D417/10 ,  C07D417/12

Abstract: Disclosed are compounds of Formula (I)





pharmaceutically acceptable salts thereof are defined herein, and pharmaceutical compositions thereof and combinations thereof, and methods of using the same as inhibitors of protein tyrosine phosphatases (PTPN2). These compounds are useful in treating cancer and diseases susceptible to PNPT2 inhibition.