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公开(公告)号:US20060287297A1
公开(公告)日:2006-12-21
申请号:US11424311
申请日:2006-06-15
申请人: Bart DeCorte , Li Liu , Mark McDonnell , Jim McNally
发明人: Bart DeCorte , Li Liu , Mark McDonnell , Jim McNally
IPC分类号: A61K31/55 , A61K31/506
CPC分类号: C07D451/02 , C07D405/04 , C07D451/14
摘要: The invention is directed to compounds of Formula (I) useful as delta and mu opioid receptor modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
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公开(公告)号:US20090275610A1
公开(公告)日:2009-11-05
申请号:US12500706
申请日:2009-07-10
申请人: Bart DeCorte , Li Liu , Mark McDonnell , Jim McNally
发明人: Bart DeCorte , Li Liu , Mark McDonnell , Jim McNally
IPC分类号: A61K31/4725 , C07D405/14 , A61K31/403 , A61K31/4439 , A61P25/00
CPC分类号: C07D451/02 , C07D405/04 , C07D451/14
摘要: The invention is directed to compounds of Formula (I) useful as delta and mu opioid receptor modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
摘要翻译: 本发明涉及用作δ和μ阿片样物质受体调节剂的式(I)化合物。 还描述了使用本发明的化合物治疗轻度至重度疼痛和各种疾病的药物和兽医组合物和方法。
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公开(公告)号:US07582650B2
公开(公告)日:2009-09-01
申请号:US11424311
申请日:2006-06-15
申请人: Bart DeCorte , Li Liu , Mark McDonnell , Jim McNally
发明人: Bart DeCorte , Li Liu , Mark McDonnell , Jim McNally
IPC分类号: C07D221/22 , A61K31/46
CPC分类号: C07D451/02 , C07D405/04 , C07D451/14
摘要: The invention is directed to compounds of Formula (I) useful as delta and mu opioid receptor modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
摘要翻译: 本发明涉及用作δ和μ阿片样物质受体调节剂的式(I)化合物。 还描述了使用本发明的化合物治疗轻度至重度疼痛和各种疾病的药物和兽医组合物和方法。
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