专利检索 ap:("Bavarian Nordic A/S") AND inv:"Jose Medina Echeverz" 第 1 页

1.

发明公开
Combination Therapy for Treating Cancer with an Intravenous Administration of a Recombinant MVA and an Immune Checkpoint Antagonist or Agonist 审中-公开

公开(公告)号：US20240269254A1

公开(公告)日：2024-08-15

申请号：US17282774

申请日：2019-10-04

申请人： Bavarian Nordic A/S

发明人： Henning Lauterbach , Jose Medina Echeverz , Maria Hinterberger

IPC分类号： A61K39/00 , A61P35/00

CPC分类号： A61K39/00119 , A61K39/001106 , A61P35/00 , A61K2039/5254 , A61K2039/5256 , A61K2039/545 , A61K2039/55516 , C12N2710/24134 , C12N2710/24171

摘要： The invention relates to a pharmaceutical combination and related methods for reducing tumor volume and/or increasing the survival of a cancer patient. The combination comprises an intravenous administration of a recombinant MVA encoding CD40L and an administration of an antagonist or agonist of an immune checkpoint molecule.