公开(公告)号：US11472803B2

公开(公告)日：2022-10-18

申请号：US17161201

申请日：2021-01-28

申请人： Bayer Aktiengesellschaft ,  Bayer Pharma Aktiengesellschaft

发明人： Henrik Teller ,  Alexandros Vakalopoulos ,  Melissa Boultadakis Arapinis ,  Alexander Straub ,  Hanna Tinel ,  Markus Brechmann ,  Matthias Beat Wittwer ,  Maximillian Andreas Kullmann ,  Till Freudenberger ,  Thomas Mondritzki ,  Tobias Marquardt

IPC分类号： C07D471/04 ,  A61P9/06 ,  A61K31/4375 ,  A61K31/551 ,  A61K45/06 ,  C07D491/107 ,  C07D519/00 ,  A61P9/00 ,  A61P13/00

摘要： The present application relates to novel 7-substituted 1-arylnaphthyridine-3-carboxamides, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prevention of diseases, and to their use for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders and/or renal disorders.

公开(公告)号：US10927109B2

公开(公告)日：2021-02-23

申请号：US16333079

申请日：2017-09-06

申请人： Bayer Aktiengesellschaft ,  Bayer Pharma Aktiengesellschaft

发明人： Henrik Teller ,  Alexandros Vakalopoulos ,  Melissa Boultadakis Arapinis ,  Alexander Straub ,  Hanna Tinel ,  Markus Brechmann ,  Matthias Beat Wittwer ,  Maximilian Andreas Kullmann ,  Till Freudenberger ,  Thomas Mondritzki ,  Tobias Marquardt

IPC分类号： C07D471/04 ,  A61K31/4375 ,  A61P9/06 ,  A61K31/551 ,  A61K45/06 ,  C07D491/107 ,  C07D519/00 ,  A61P9/00 ,  A61P13/00

摘要： The present application relates to novel 7-substituted 1-arylnaphthyridine-3-carboxamides, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prevention of diseases, and to their use for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders and/or renal disorders.