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1.发明授权Combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases 有权抗胆碱能药和白细胞三烯受体拮抗剂的组合用于治疗呼吸系统疾病公开(公告)号：US08268864B2
公开(公告)日：2012-09-18
申请号：US11376615
申请日：2006-03-16
申请人： Beatrix Fyrnys , Torsten Hoffmann , Mario Weingart , Istvan Szelenyi , Peter Jurgen Cnota , Ullrich Munzel , Ursula Petzold , Joachim Maus
发明人： Beatrix Fyrnys , Torsten Hoffmann , Mario Weingart , Istvan Szelenyi , Peter Jurgen Cnota , Ullrich Munzel , Ursula Petzold , Joachim Maus
IPC分类号： A01N43/42 , A01N43/36 , A61K31/47 , A61K31/40 , C07D207/00 , C07D453/04
CPC分类号： A61K31/40 , A61K31/4015 , A61K31/47 , A61K45/06 , A61K2300/00
摘要： Pharmaceutical compositions comprising an anticholinergic and at least one leukotriene inhibitor for treatment of respiratory diseases, including allergic rhinitis, bronchial asthma, COPD and common cold, and methods of treatment.
摘要翻译： 包含抗胆碱能药和至少一种用于治疗呼吸系统疾病的白三烯抑制剂的药物组合物，包括过敏性鼻炎，支气管哮喘，COPD和感冒，以及治疗方法。
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2.发明授权Combination of anticholinergics, β2-adrenoceptor agonists, antileukotrienes (leukotriene receptor antagonists), glucocorticoids and/or phosphodiesterase 4 inhibitors for the treatment of inflammatory diseases 有权抗胆碱能药，β2-肾上腺素能受体激动剂，抗白细胞三烯（白三烯受体拮抗剂），糖皮质激素和/或磷酸二酯酶4抑制剂用于治疗炎性疾病公开(公告)号：US08518918B2
公开(公告)日：2013-08-27
申请号：US13242241
申请日：2011-09-23
IPC分类号： A61K31/56 , A61K31/16 , A61K31/40 , A61K31/135
CPC分类号： A61K31/40 , A61K9/0075 , A61K9/008 , A61K31/167 , A61K31/4015 , A61K31/58 , A61K45/06 , A61K2300/00
摘要： The invention relates to novel combinations based on anticholinergics, β2-adrenoceptor agonists, PDE 4 Inhibitors, glucocorticoids, and leukotriene-receptor antagonists, process for their production and their use for the treatment of inflammatory diseases, preferably respiratory diseases as bronchial asthma and chronic obstructive pulmonary diseases (COPD) or rheumatic or autoimmune diseases.
摘要翻译： 本发明涉及基于抗胆碱能药物，β2-肾上腺素能受体激动剂，PDE4抑制剂，糖皮质激素和白三烯受体拮抗剂的新型组合，其生产方法及其用于治疗炎性疾病，优选呼吸系统疾病作为支气管哮喘和慢性阻塞性 肺部疾病（COPD）或风湿性或自身免疫性疾病。
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3.发明授权Combination of anticholineric and β mimetics for the treatment of respiratory diseases 有权抗胆碱药与组合 用于治疗呼吸系统疾病的模拟物质公开(公告)号：US07985766B2
公开(公告)日：2011-07-26
申请号：US11882109
申请日：2007-07-30
IPC分类号： A61K31/4015 , A61K31/167
CPC分类号： A61K45/06 , A61K9/0075 , A61K9/008 , A61K31/138 , A61K31/167 , A61K31/401 , A61K31/4015 , A61K2300/00
摘要： The present invention describes a combination of an anticholinergic, such as R,R-glycopyrrolate, and a β mimetic, such as tormoterol, for the treatment of respiratory diseases including airway inflammation or obstruction such as chronic obstructive pulmonary disease (COPD) and asthma.
摘要翻译： 本发明描述了抗胆碱能药物如R，R-格隆溴铵和一种bgr的组合; 模拟物，如泰莫曲醇，用于治疗呼吸道疾病，包括呼吸道炎症或梗阻，如慢性阻塞性肺疾病（COPD）和哮喘。
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4.发明申请Combination of Anticholinergics and Glucocorticoids for the Long-Term Treatment of Asthma and COPD 审中-公开组合抗胆碱能药物和糖皮质激素用于长期治疗哮喘和COPD公开(公告)号：US20080300226A1
公开(公告)日：2008-12-04
申请号：US12189598
申请日：2008-08-11
摘要： The present invention describes the combination of topically inhaled medicinal formulations comprising an anticholinergic component and a glucocorticosteroid component and its use in the symptomatic and prophylactic treatment of diseases of the respiratory tract, especially with an obstructive component or underlying inflammation like asthma and chronic obstructive pulmonary disease (COPD). It further comprises the presentation of this combination in a locally applied (inhaled) formulation and application in an inhalation device for instance in the Novolizer®.
摘要翻译： 本发明描述了包含抗胆碱能成分和糖皮质激素成分的局部吸入药物制剂的组合及其在对呼吸道疾病的症状和预防性治疗中的用途，特别是阻塞性成分或潜在炎症如哮喘和慢性阻塞性肺病 （COPD）。 它还包括将这种组合在局部施用（吸入）制剂中的应用和例如在Novolizer中的吸入装置中的应用。
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