公开(公告)号：US11932613B2

公开(公告)日：2024-03-19

申请号：US16994855

申请日：2020-08-17

申请人： Bijukumar Gopinathan Pillai ,  Sima Mirilashvili ,  Yaniv Barda ,  Bhavinkumar P. Hamirani ,  Bhoopal Meka ,  Sreedevi Mannam

发明人： Bijukumar Gopinathan Pillai ,  Sima Mirilashvili ,  Yaniv Barda ,  Bhavinkumar P. Hamirani ,  Bhoopal Meka ,  Sreedevi Mannam

IPC分类号： C07D239/52 ,  C07D239/69 ,  C07D275/06

CPC分类号： C07D275/06 ,  C07D239/52 ,  C07D239/69

摘要： A process for preparing, 1,1,3-trioxo-1,2-benzothiazole-6-carboxamide of formula (I) comprising: (a) oxidizing 2,5-dimethyl-benzenesulfonamide of formula (II) in the presence of an oxidizing agent to receive 2-sulfamoyl-terephthalic acid of formula (III); (b) converting the formed 2-sulfamoyl-terephthalic acid of formula (III) to receive 2-sulfonoyl-terephthalic acid derivative of formula (IV); and (c) reacting the resulting 2-sulfamoyl-terephthalic acid derivative of formula (IV) with ammonia (NH3) or ammonium containing-salt; wherein R represents OR′ or CI and R′ represents a branched or non-branched C1-C12 alkyl.

公开(公告)号：US20200157067A1

公开(公告)日：2020-05-21

申请号：US16066965

申请日：2016-12-28

申请人： Bijukumar Gopinathan Pillai ,  Sima Mirilashvili ,  Yaniv Barda ,  Bhavinkumar P. Hamirani ,  Bhoopal Meka ,  Sreedevi Mannam

发明人： Bijukumar Gopinathan Pillai ,  Sima Mirilashvili ,  Yaniv Barda ,  Bhavinkumar P. Hamirani ,  Bhoopal Meka ,  Sreedevi Mannam

IPC分类号： C07D275/06 ,  C07D239/69

摘要： A process for preparing, 1,1,3-trioxo-1,2-benzothiazole-6-carboxamide of formula (I) comprising: (a) oxidizing 2,5-dimethyl-benzenesulfonamide of formula (II) in the presence of an oxidizing agent to receive 2-sulfamoyl-terephthalic acid of formula (III); (b) converting the formed 2-sulfamoyl-terephthalic acid of formula (III) to receive 2-sulfamoyl-terephthalic acid derivative of formula (IV); and (c) reacting the resulting 2-sulfamoyl-terephthalic acid derivative of formula (IV) with ammonia (NH3) or ammonium containing-salt; wherein R represents OR′ or CI and R′ represents a branched or non-branched C1-C12 alkyl.

公开(公告)号：US20210347746A1

公开(公告)日：2021-11-11

申请号：US16994855

申请日：2020-08-17

申请人： Bijukumar Gopinathan Pillai ,  Sima Mirilashvili ,  Yaniv Barda ,  Bhavinkumar P. Hamirani ,  Bhoopal Meka ,  Sreedevi Mannam

发明人： Bijukumar Gopinathan Pillai ,  Sima Mirilashvili ,  Yaniv Barda ,  Bhavinkumar P. Hamirani ,  Bhoopal Meka ,  Sreedevi Mannam

IPC分类号： C07D275/06 ,  C07D239/52

摘要： A process for preparing, 1,1,3-trioxo-1,2-benzothiazole-6-carboxamide of formula (I) comprising: (a) oxidizing 2,5-dimethyl-benzenesulfonamide of formula (II) in the presence of an oxidizing agent to receive 2-sulfamoyl-terephthalic acid of formula (III); (b) converting the formed 2-sulfamoyl-terephthalic acid of formula (III) to receive 2-sulfamoyl-terephthalic acid derivative of formula (IV); and (c) reacting the resulting 2-sulfamoyl-terephthalic acid derivative of formula (IV) with ammonia (NH3) or ammonium containing-salt; wherein R represents OR′ or Cl and R′ represents a branched or non-branched C1-C12 alkyl.

公开(公告)号：US10774055B2

公开(公告)日：2020-09-15

申请号：US16066965

申请日：2016-12-28

申请人： Bijukumar Gopinathan Pillai ,  Sima Mirilashvili ,  Yaniv Barda ,  Bhavinkumar P. Hamirani ,  Bhoopal Meka ,  Sreedevi Mannam

发明人： Bijukumar Gopinathan Pillai ,  Sima Mirilashvili ,  Yaniv Barda ,  Bhavinkumar P. Hamirani ,  Bhoopal Meka ,  Sreedevi Mannam

IPC分类号： C07D275/06 ,  C07D239/69

摘要： A process for preparing, 1,1,3-trioxo-1,2-benzothiazole-6-carboxamide of formula (I) comprising: (a) oxidizing 2,5-dimethyl-benzenesulfonamide of formula (II) in the presence of an oxidizing agent to receive 2-sulfamoyl-terephthalic acid of formula (III); (b) converting the formed 2-sulfamoyl-terephthalic acid of formula (III) to receive 2-sulfamoyl-terephthalic acid derivative of formula (IV); and (c) reacting the resulting 2-sulfamoyl-terephthalic acid derivative of formula (IV) with ammonia (NH3) or ammonium containing-salt; wherein R represents OR′ or CI and R′ represents a branched or non-branched C1-C12 alkyl.