公开(公告)号：US06905885B2

公开(公告)日：2005-06-14

申请号：US09880515

申请日：2001-06-12

申请人： Billy W. Colston ,  Matthew Everett ,  Fred P. Milanovich ,  Steve B. Brown ,  Kodumudi Vendateswaran ,  Jonathan N. Simon

发明人： Billy W. Colston ,  Matthew Everett ,  Fred P. Milanovich ,  Steve B. Brown ,  Kodumudi Vendateswaran ,  Jonathan N. Simon

IPC分类号： G01N33/543 ,  G01N33/53

CPC分类号： G01N33/54313

摘要： A portable pathogen detection system that accomplishes on-site multiplex detection of targets in biological samples. The system includes: microbead specific reagents, incubation/mixing chambers, a disposable microbead capture substrate, and an optical measurement and decoding arrangement. The basis of this system is a highly flexible Liquid Array that utilizes optically encoded microbeads as the templates for biological assays. Target biological samples are optically labeled and captured on the microbeads, which are in turn captured on an ordered array or disordered array disposable capture substrate and then optically read.

摘要翻译： 便携式病原体检测系统，实现了生物样品中靶标的现场多重检测。 该系统包括：微珠特异性试剂，孵育/混合室，一次性微珠捕获底物和光学测量和解码装置。 该系统的基础是高度灵活的液体阵列，其利用光学编码的微珠作为生物测定的模板。 目标生物样品被光学标记并捕获在微珠上，微珠又依次在有序阵列或无序阵列一次性捕获基底上捕获，然后光学读取。