公开(公告)号：US09889394B2

公开(公告)日：2018-02-13

申请号：US14266389

申请日：2014-04-30

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Richard Day ,  Michael Burcher ,  Nathan Wrench ,  Marek Myszko ,  Matthew Hayes

IPC: G01N1/22 ,  B01D29/62 ,  G01N1/34 ,  B01D29/72 ,  G01N1/40

CPC classification number: B01D29/62 ,  B01D29/72 ,  G01N1/34 ,  G01N2001/4088

Abstract: A filter device having a sonotrode connected to a filtration assembly. The filtration assembly has a filter body having a fluid passage. The filter body has a filter across the fluid passage. The filter assembly has a resonant frequency and the sonotrode is adapted to vibrate the filter assembly at or near the resonant frequency.

公开(公告)号：US20140261868A1

公开(公告)日：2014-09-18

申请号：US14213001

申请日：2014-03-14

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Nathan Wrench ,  William Mainwaring-Burton ,  Chris Butcher ,  Nick Harrison

IPC: G01N30/32

CPC classification number: G01N30/32 ,  B67D7/0255 ,  G01N30/16 ,  G01N30/22 ,  G01N30/88 ,  G01N2030/8881 ,  Y10T137/9029

Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.

Abstract translation: 公开了一种用于高压液相色谱（HPLC）仪器的容器组件，其中容器组件当耦合到加压气体源时以正压力向HPLC仪器提供流体介质。 容器组件具有外部外部容器壳体，用于保持流体介质的内部流体容器，外部外部容器壳体和内部流体容器之间的间隙容积，用于将体积流体连接到加压气体源的端口和端口 用于将内部流体容器流体连接到HPLC仪器。 随着间隙体积中的加压气体的增加，流体介质以正压力流出连接到内部流体袋和容器组件的端口。 还公开了一种结合容器组件的系统及其使用方法。

公开(公告)号：US11525813B2

公开(公告)日：2022-12-13

申请号：US15885555

申请日：2018-01-31

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Nathan Wrench ,  William Mainwaring-Burton ,  Chris Butcher ,  Nick Harrison

IPC: G01N30/32 ,  B67D7/02 ,  G01N30/16 ,  G01N30/22 ,  G01N30/88

Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.

公开(公告)号：US09921193B2

公开(公告)日：2018-03-20

申请号：US14213001

申请日：2014-03-14

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Nathan Wrench ,  William Mainwaring-Burton ,  Chris Butcher ,  Nick Harrison

IPC: G01N30/32 ,  G01N30/16 ,  G01N30/22 ,  G01N30/88 ,  B67D7/02

CPC classification number: G01N30/32 ,  B67D7/0255 ,  G01N30/16 ,  G01N30/22 ,  G01N30/88 ,  G01N2030/8881 ,  Y10T137/9029

Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.

公开(公告)号：US20140326080A1

公开(公告)日：2014-11-06

申请号：US14266389

申请日：2014-04-30

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Richard Day ,  Michael Burcher ,  Nathan Wrench ,  Marek Myszko ,  Matthew Hayes

IPC: B01D29/62

CPC classification number: B01D29/62 ,  B01D29/72 ,  G01N1/34 ,  G01N2001/4088

Abstract: A filter device having a sonotrode connected to a filtration assembly. The filtration assembly has a filter body having a fluid passage. The filter body has a filter across the fluid passage. The filter assembly has a resonant frequency and the sonotrode is adapted to vibrate the filter assembly at or near the resonant frequency.

Abstract translation: 具有连接到过滤组件的超声波发生器的过滤装置。 过滤组件具有具有流体通道的过滤器本体。 过滤器本体具有穿过流体通道的过滤器。 过滤器组件具有谐振频率，并且超声波发生器适于使谐振频率处于或接近谐振频率处的振动。

公开(公告)号：US20180238839A1

公开(公告)日：2018-08-23

申请号：US15885555

申请日：2018-01-31

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Nathan Wrench ,  William Mainwaring-Burton ,  Chris Butcher ,  Nick Harrison

IPC: G01N30/32 ,  B67D7/02 ,  G01N30/22 ,  G01N30/88 ,  G01N30/16

CPC classification number: G01N30/32 ,  B67D7/0255 ,  G01N30/16 ,  G01N30/22 ,  G01N30/88 ,  G01N2030/8881 ,  Y10T137/9029

Abstract: A container assembly for use with a high-pressure liquid chromatography (HPLC) instrument is disclosed, in which the container assembly, when coupled to a source of pressurized gas, provides fluid medium to the HPLC instrument at positive pressure. The container assembly has an external exterior container shell, an internal fluid container for holding fluid medium, an interstitial volume between the external exterior container shell and the internal fluid container, a port for fluidly connecting the volume to a pressurized gas source, and a port for fluidly connecting the internal fluid container to the HPLC instrument. As a pressurized gas in the interstitial volume increases, fluid medium flows out of the port connected to the internal fluid bag and container assembly at a positive pressure. A system incorporating the container assembly, and method of use of the same, are also disclosed.

公开(公告)号：US09320988B2

公开(公告)日：2016-04-26

申请号：US14209974

申请日：2014-03-13

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Nathan Wrench ,  William Mainwaring-Burton

IPC: B01D19/00

CPC classification number: B01D19/0031

Abstract: Disclosed herein is an apparatus for debubbling or degassing a liquid. The apparatus includes a tube with a hollow lumen and a gas-permeable, liquid-impermeable wall surrounding the lumen. Also disclosed is a method for performing the debubbling or degassing, wherein the liquid is passed through the tube and gas is allowed to escape through the wall of the tube. The application additionally discloses a system for debubbling or degassing a liquid, wherein a pump is connected to the upstream end of the tube and a device to impede the flow of liquid out the tube is connected to the downstream end.

Abstract translation: 本文公开了一种用于对液体进行脱泡或脱气的装置。 该装置包括具有中空腔的管和围绕腔的透气的液体不可渗透的壁。 还公开了一种用于进行脱泡或脱气的方法，其中液体通过管，并且允许气体通过管的壁逸出。 该应用还公开了一种用于对液体进行脱泡或脱气的系统，其中泵连接到管的上游端，并且阻止液体流出管的装置连接到下游端。

公开(公告)号：US20140260970A1

公开(公告)日：2014-09-18

申请号：US14209974

申请日：2014-03-13

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Nathan Wrench ,  William Mainwaring-Burton

IPC: B01D19/00

CPC classification number: B01D19/0031

Abstract: Disclosed herein is an apparatus for debubbling or degassing a liquid. The apparatus includes a tube with a hollow lumen and a gas-permeable, liquid-impermeable wall surrounding the lumen. Also disclosed is a method for performing the debubbling or degassing, wherein the liquid is passed through the tube and gas is allowed to escape through the wall of the tube. The application additionally discloses a system for debubbling or degassing a liquid, wherein a pump is connected to the upstream end of the tube and a device to impede the flow of liquid out the tube is connected to the downstream end.

Abstract translation: 本文公开了一种用于对液体进行脱泡或脱气的装置。 该装置包括具有中空腔的管和围绕内腔的透气的液体不可渗透的壁。 还公开了一种用于进行脱泡或脱气的方法，其中液体通过管，并且允许气体通过管的壁逸出。 该应用还公开了一种用于对液体进行脱泡或脱气的系统，其中泵连接到管的上游端，并且阻止液体流出管的装置连接到下游端。