公开(公告)号：US20150316479A1

公开(公告)日：2015-11-05

申请号：US14699755

申请日：2015-04-29

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： EVAN THRUSH ,  STEVE SWIHART ,  Neeraj Bhatt

IPC: G01N21/64

CPC classification number: G01N21/6456 ,  G01N21/6486 ,  G01N2021/6439 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2201/062 ,  G01N2201/0627 ,  G01N2201/0638 ,  G01N2201/12

Abstract: An imaging assembly and processing system that includes a sample platform having a target region which can hold a sample, where the sample can be marked with fluorescent or phosphorescent markers. The imaging assembly can have an excitation light module proximate to the sample platform that emits light to excite the markers, and a lens module positioned to receive emission light from excited markers in target region. At least one series filter assembly or interference filter can be arranged in front of, behind, or both in front of and behind the lens module. The assembly includes a light sensor and a processor and imaging module configured to process data captured by the light sensor. Images of the sample are generated based on the emission light from the sample that transmit through and are filtered by the lens assembly and series filter assembly or interference filter.

Abstract translation: 一种成像组件和处理系统，其包括具有可容纳样品的目标区域的样品平台，其中可以用荧光或磷光标记物标记样品。 成像组件可以具有靠近样本平台的激发光模块，其发射光以激发标记;以及透镜模块，其定位成接收来自目标区域中的激发标记的发射光。 至少一个串联滤波器组件或干涉滤波器可以布置在透镜模块的前面，后面或者两者之间。 组件包括光传感器，以及被配置为处理由光传感器捕获的数据的处理器和成像模块。 基于来自样品的发射光，通过透镜组件和串联滤光器组件或干涉滤光器滤光而产生样品的图像。

公开(公告)号：US09841378B2

公开(公告)日：2017-12-12

申请号：US14699755

申请日：2015-04-29

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： Evan Thrush ,  Steve Swihart ,  Neeraj Bhatt

IPC: G01N21/64

CPC classification number: G01N21/6456 ,  G01N21/6486 ,  G01N2021/6439 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2201/062 ,  G01N2201/0627 ,  G01N2201/0638 ,  G01N2201/12

Abstract: An imaging assembly and processing system that includes a sample platform having a target region which can hold a sample, where the sample can be marked with fluorescent or phosphorescent markers. The imaging assembly can have an excitation light module proximate to the sample platform that emits light to excite the markers, and a lens module positioned to receive emission light from excited markers in target region. At least one series filter assembly or interference filter can be arranged in front of, behind, or both in front of and behind the lens module. The assembly includes a light sensor and a processor and imaging module configured to process data captured by the light sensor. Images of the sample are generated based on the emission light from the sample that transmit through and are filtered by the lens assembly and series filter assembly or interference filter.

公开(公告)号：US20140312247A1

公开(公告)日：2014-10-23

申请号：US14252406

申请日：2014-04-14

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Clayton T. McKee ,  William Strong ,  Neeraj Bhatt

IPC: G01N21/64

CPC classification number: G01N21/6428 ,  G01N21/6456

Abstract: Systems and methods for substantially simultaneously exciting a fluorescently labeled specimen and capturing fluorescent light emitted therefrom using a smartphone, tablet, or similar mobile computing device, are disclosed herein. The system includes a light-emitting diode (“LED”) light source coupled with the smartphone to excite the specimen and an imaging device coupled with the smartphone to capture fluorescent light emitted from the specimen. The system further includes a hood adapted to be coupled with the smartphone that has an excitation filter configured to produce a first wavelength of electromagnetic radiation to strike the specimen when light from the LED light source passes through it and an emission filter configured to receive the light emitted from the specimen and to produce a second wavelength of electromagnetic radiation to be captured by the imaging device.

Abstract translation: 本文公开了用于基本上同时激发荧光标记的样本并且使用智能电话，平板电脑或类似的移动计算设备捕获从其发射的荧光的系统和方法。 该系统包括与智能手机耦合以激发样本的发光二极管（“LED”）光源和与智能手机耦合的成像装置以捕获从样品发射的荧光。 该系统还包括适于与智能电话耦合的罩，其具有激励滤波器，该激励滤波器被配置为产生第一波长的电磁辐射以在来自LED光源的光穿过其时撞击样本;以及发射滤波器，被配置为接收光 从样品发射并产生将被成像装置捕获的第二波长的电磁辐射。