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公开(公告)号：US20180169236A1
公开(公告)日：2018-06-21
申请号：US15675148
申请日：2017-08-11
Applicant: BioNTech AG
Inventor： Ozlem Tureci , Ugur Sahin , Sandra Schneider , Gerd Helftenbein , Volker Schluter , Dirk Usener , Philippe Thiel , Michael Koslowski
IPC: A61K39/395 , C07K16/30 , C07K16/28 , A61K45/06
Abstract: The invention relates to the identification of gene products that are the result of tumor-associated expression and the nucleic acids encoding the same. The invention also relates to the therapy and diagnosis of diseases wherein these gene products are the result of an aberrant tumor-associated expression. The invention also relates to the proteins, polypeptides and peptides that are the result of tumor-associated expression and to the nucleic acids encoding the same.
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Patent Agency Ranking
公开(公告)号：US09194004B2
公开(公告)日：2015-11-24
申请号：US13864411
申请日：2013-04-17
Applicant: BioNTech AG
Inventor： Ugur Sahin , Ozlem Tureci , Michael Koslowski , Gerd Helftenbein , Dirk Usener , Volker Schluter
IPC: C12Q1/68 , G01N33/574
CPC classification number: G01N33/57492 , C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , G06F19/22
Abstract: The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.
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公开(公告)号：US10724103B2
公开(公告)日：2020-07-28
申请号：US15675148
申请日：2017-08-11
Applicant: BioNTech AG
Inventor： Ozlem Tureci , Ugur Sahin , Sandra Schneider , Gerd Helftenbein , Volker Schluter , Dirk Usener , Philippe Thiel , Michael Koslowski
IPC: C12Q1/686 , C12Q1/6886 , C07K14/47 , A61K39/395 , A61K45/06 , C07K16/28 , C07K16/30 , G01N33/53
Abstract: The invention relates to the identification of gene products that are the result of tumor-associated expression and the nucleic acids encoding the same. The invention also relates to the therapy and diagnosis of diseases wherein these gene products are the result of an aberrant tumor-associated expression. The invention also relates to the proteins, polypeptides and peptides that are the result of tumor-associated expression and to the nucleic acids encoding the same.
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公开(公告)号：US10302647B2
公开(公告)日：2019-05-28
申请号：US14887979
申请日：2016-03-07
Applicant: BioNTech AG
Inventor： Ugur Sahin , Ozlem Tureci , Michael Koslowski , Gerd Helftenbein , Dirk Usener , Volker Schluter
IPC: C12Q1/686 , G01N33/574 , C12Q1/6886 , G06F19/22
Abstract: The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.
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5.发明申请Identification of Surface-Associated Antigens for Tumor Diagnosis and Therapy 审中-公开鉴定表面相关抗原的肿瘤诊断和治疗公开(公告)号：US20170052187A1
公开(公告)日：2017-02-23
申请号：US14887979
申请日：2016-03-07
Applicant: BioNTech AG
Inventor： Ugur Sahin , Ozlem Tureci , Michael Koslowski , Gerd Helftenbein , Dirk Usener , Volker Schluter
IPC: G01N33/574 , G06F19/22 , C12Q1/68
CPC classification number: G01N33/57492 , C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , G06F19/22
Abstract: The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.
Abstract translation: 本发明涉及鉴定肿瘤相关基因产物并编码其核酸。 还公开了与肿瘤相关表达的肿瘤相关遗传产物异常表达的疾病的治疗和诊断，以及用于所述蛋白质，多肽和肽的编码核酸的蛋白质，多肽和肽。
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6.发明申请IDENTIFICATION OF SURFACE-ASSOCIATED ANTIGENS FOR TUMOR DIAGNOSIS AND THERAPY 有权用于肿瘤诊断和治疗的表面相关抗原的鉴定公开(公告)号：US20140017679A1
公开(公告)日：2014-01-16
申请号：US13864411
申请日：2013-04-17
Applicant: BioNTech AG
Inventor： Ugur Sahin , Ozlem Tureci , Michael Koslowski , Gerd Helftenbein , Dirk Usener , Volker Schluter
IPC: C12Q1/68
CPC classification number: G01N33/57492 , C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , G06F19/22
Abstract: The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.
Abstract translation: 本发明涉及鉴定肿瘤相关基因产物并编码其核酸。 还公开了与肿瘤相关表达的肿瘤相关遗传产物异常表达的疾病的治疗和诊断，以及用于所述蛋白质，多肽和肽的编码核酸的蛋白质，多肽和肽。
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