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公开(公告)号:US20240408032A1
公开(公告)日:2024-12-12
申请号:US18689727
申请日:2022-09-09
Applicant: BioNTech SE
Inventor: Hossam HEFESHA , Heinrich HAAS , Ferdia BATES , Christian HOTZ , Katalin KARIKÓ
Abstract: The present disclosure relates to RNA particles comprising phospholipids with a phosphatidylserine head group for delivering RNA to target tissues after administration, in particular after parenteral, intratumoral, or peritumoral administration, and compositions comprising such RNA particles. The present disclosure also relates to methods for preparing RNA particles described herein.