公开(公告)号：US20140323570A1

公开(公告)日：2014-10-30

申请号：US14264653

申请日：2014-04-29

Applicant: Biogen Idec MA Inc.

Inventor： Ralf GOLD

IPC: A61K31/225

CPC classification number: A61K31/225

Abstract: Methods of treating neurological disorders characterized by extensive demyelination and/or axonal loss are provided. Examples of such disorders include secondary progressive multiple sclerosis and Devic's disease. The disclosed methods include administering to a subject having such a disorder a therapeutically effective amount of, for example, dimethyl fumarate or monomethyl fumarate.

Abstract translation: 提供治疗以广泛脱髓鞘和/或轴突损失为特征的神经障碍的方法。 这种病症的实例包括继发性进行性多发性硬化症和Devic氏病。 所公开的方法包括向具有这种病症的受试者施用治疗有效量的例如富马酸二甲酯或富马酸单甲酯。

公开(公告)号：US20130302410A1

公开(公告)日：2013-11-14

申请号：US13826354

申请日：2013-03-14

Applicant: Biogen Idec MA Inc.

Inventor： Ralf GOLD

IPC: A61K31/225

CPC classification number: A61K31/225

Abstract: Methods of treating neurological disorders characterized by extensive demyelination and/or axonal loss are provided. Examples of such disorders include secondary progressive multiple sclerosis and Devic's disease. The disclosed methods include administering to a subject having such a disorder a therapeutically effective amount of, for example, dimethyl fumarate or monomethyl fumarate.

Abstract translation: 提供治疗以广泛脱髓鞘和/或轴突损失为特征的神经障碍的方法。 这种病症的实例包括继发性进行性多发性硬化症和Devic氏病。 所公开的方法包括向具有这种病症的受试者施用治疗有效量的例如富马酸二甲酯或富马酸单甲酯。