公开(公告)号：US20210069307A1

公开(公告)日：2021-03-11

申请号：US16995173

申请日：2020-08-17

Applicant: Bioverativ Therapeutics Inc.

Inventor： Brian M. THOME ,  Cherie PARKHURST-LANG ,  Brandon W. LEVEILLE

IPC: A61K38/48 ,  F26B5/06 ,  A61K47/18 ,  A61K9/00 ,  A61K9/19 ,  A61K47/22 ,  A61K47/26

Abstract: The present invention provides, among other things, pre-lyophilization formulations, reconstituted formulations, and lyophilate powder compositions comprising a Factor IX (FIX) polypeptide. The present invention also provides lyophilization methods for producing lyophilate powder comprising a FIX polypeptide.

公开(公告)号：US20250121042A1

公开(公告)日：2025-04-17

申请号：US18894851

申请日：2024-09-24

Applicant: Bioverativ Therapeutics Inc.

Inventor： Brian M. THOME ,  Cherie PARKHURST-LANG ,  Brandon W. LEVEILLE

IPC: A61K38/48 ,  A61K9/00 ,  A61K9/19 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26 ,  F26B5/06

Abstract: The present invention provides, among other things, pre-lyophilization formulations, reconstituted formulations, and lyophilate powder compositions comprising a Factor IX (FIX) polypeptide. The present invention also provides lyophilization methods for producing lyophilate powder comprising a FIX polypeptide.