公开(公告)号：US20250163046A1

公开(公告)日：2025-05-22

申请号：US18759719

申请日：2024-06-28

Applicant: Bristol-Myers Squibb Company

Inventor： Brian Edward FINK ,  Pravin S. SHIRUDE ,  Amit Kumar CHATTOPADHYAY ,  Laxmi Narayan NANDA ,  Vishweshwaraiah BALIGAR ,  Balaji SESHADRI ,  T.G. Murali DHAR ,  Li-Qiang SUN ,  Zhizhen Barbara ZHENG ,  Manoranjan PANDA ,  Maximilian David PALKOWITZ ,  Sirish Kaushik LAKKARAJU ,  Moloy BANERJEE

IPC: C07D471/04 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/538 ,  A61K31/5386 ,  A61K31/553 ,  A61K31/554 ,  A61P35/00 ,  C07D519/00

Abstract: The present disclosure provides KRAS inhibitors. Methods of treating cancers using the compounds are also provided.

公开(公告)号：US20250154148A1

公开(公告)日：2025-05-15

申请号：US18759708

申请日：2024-06-28

Applicant: Bristol-Myers Squibb Company

Inventor： Brian Edward FINK ,  Pravin S. SHIRUDE ,  Amit Kumar CHATTOPADHYAY ,  Laxmi Narayan NANDA ,  Vishweshwaraiah BALIGAR ,  Balaji SESHADRI ,  T.G. Murali DHAR ,  Li-Qiang SUN ,  Zhizhen Barbara ZHENG ,  Manoranjan PANDA ,  Maximilian David PALKOWITZ ,  Sirish Kaushik LAKKARAJU ,  Moloy BANERJEE

IPC: C07D471/04 ,  A61K31/553 ,  A61P35/00

Abstract: The present disclosure provides KRAS inhibitors. Methods of treating cancers using the compounds are also provided.