公开(公告)号：US20190112293A1

公开(公告)日：2019-04-18

申请号：US16211848

申请日：2018-12-06

Applicant: Bristol-Myers Squibb Company

Inventor： ELIZABETH ANNE JURICA ,  Zhenqiu Hong

IPC: C07D401/14 ,  C07D401/12 ,  A61K31/506 ,  A61K31/4545 ,  A61K45/06 ,  A61K31/454

Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

公开(公告)号：US20200299267A1

公开(公告)日：2020-09-24

申请号：US16895058

申请日：2020-06-08

Applicant: Bristol-Myers Squibb Company

Inventor： ELIZABETH ANNE JURICA ,  Zhenqiu Hong

IPC: C07D401/14 ,  A61K31/4545 ,  A61K45/06 ,  A61K31/454 ,  A61K31/506 ,  C07D401/12

Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.