专利检索 ap:("Bristol-Myers Squibb Company") AND inv:"Laurence David TOMS" 第 1 页

1.

发明公开
LAG-3 ANTAGONIST THERAPY FOR LUNG CANCER 审中-公开

公开(公告)号：US20240101666A1

公开(公告)日：2024-03-28

申请号：US18033200

申请日：2021-10-22

申请人： Bristol-Myers Squibb Company

发明人： Laurence David TOMS , Paul Andrew BASCIANO

IPC分类号： C07K16/28 , A61K31/282 , A61K31/337 , A61K31/519 , A61K33/243 , A61P35/00

CPC分类号： C07K16/2803 , A61K31/282 , A61K31/337 , A61K31/519 , A61K33/243 , A61P35/00 , C07K16/2818 , A61K2039/507

摘要： The disclosure provides a method of treating a human subject afflicted with lung cancer with a lymphocyte activation gene-3 (LAG-3) antagonist. In some aspects, the method comprises combination of the LAG-3 antagonist with an additional therapeutic agent (e.g., a programmed death-1 pathway inhibitor) and/or anti-cancer therapy (e.g., chemotherapy such as a platinum doublet chemotherapy).