公开(公告)号：US08557274B2

公开(公告)日：2013-10-15

申请号：US11567680

申请日：2006-12-06

申请人： Bruce R. Hamaker ,  Mahesh Venktachalam ,  Genyi Zhang ,  Ali Keshavarzian ,  Devin J. Rose

发明人： Bruce R. Hamaker ,  Mahesh Venktachalam ,  Genyi Zhang ,  Ali Keshavarzian ,  Devin J. Rose

IPC分类号： A61K47/00

CPC分类号： A61K31/718 ,  A23L1/308 ,  A23L33/21 ,  A61K9/1652 ,  C08L3/02 ,  C08L5/04 ,  C08L5/06 ,  C08L2666/26

摘要： Compositions which provide slowly digestible starch and a source of fermentable dietary fiber. Microparticles in which starch is entrapped in a crosslinked matrix to provide dietary benefit. Such microparticles are used to deliver glucose to targeted regions in the small intestine for beneficial physiological effects, and fermentable dietary fiber to the colon to improve colon health and to treat diseases of the colon. Microparticles can be employed to selectively deliver fermentable dietary fiber to targeted portions of the colon. A method for making the microparticles is provided as well as methods for using the microparticles for controlled digestion of starch on ingestion in the small intestine and methods for using the microparticles to deliver dietary fiber. The microparticles with entrapped starch provide a low glycemic index and extended glucose release in food products and food ingredients. The microparticles with entrapped starch can, in particular, be used as an ingredient in foods that are to be cooked.

摘要翻译： 提供缓慢消化淀粉和可发酵膳食纤维来源的组合物。 将淀粉包埋在交联基质中以提供饮食益处的微粒。 这种微粒用于将葡萄糖输送到小肠中的目标区域以获得有益的生理作用，并将可发酵的膳食纤维输送到结肠以改善结肠健康并治疗结肠疾病。 微粒可用于选择性地将可发酵膳食纤维递送至结肠的目标部分。 提供了制备微粒的方法以及在小肠中摄取淀粉受控消化微粒的方法和使用该微粒来递送膳食纤维的方法。 具有包埋淀粉的微粒提供低的血糖指数，并延长食品和食品成分中的葡萄糖释放。 具有捕获的淀粉的微粒特别可以用作待烹饪的食品中的成分。

公开(公告)号：US20100303953A1

公开(公告)日：2010-12-02

申请号：US12791802

申请日：2010-06-01

申请人： Bruce R. Hamaker ,  Devin J. Rose ,  Ali Keshavarzian ,  Pinthip Rumpagaporn ,  Osvaldo H. Campanella

发明人： Bruce R. Hamaker ,  Devin J. Rose ,  Ali Keshavarzian ,  Pinthip Rumpagaporn ,  Osvaldo H. Campanella

IPC分类号： A23L1/308

CPC分类号： A23K10/14 ,  A23K10/30 ,  A23L33/21

摘要： The embodiments described herein provide a method for improving bowel health by increasing short chain fatty acid concentration in the colon of a mammal including administering to the mammal a composition having from about 0.1 grams to about 50 grams of a treated bran product. After administration, the treated bran product results in an increased short chain fatty acid production during fermentation in the colon as compared to untreated bran fermented in the colon.

摘要翻译： 本文所述的实施方案提供了通过增加哺乳动物结肠中的短链脂肪酸浓度来改善肠健康的方法，包括向哺乳动物施用具有约0.1克至约50克处理的麸皮产品的组合物。 给药后，与在结肠中发酵的未处理的麸皮相比，经处理的麸皮产品在结肠发酵期间导致短链脂肪酸产生增加。