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公开(公告)号：US20150051228A1
公开(公告)日：2015-02-19
申请号：US14384567
申请日：2013-03-12
发明人： Shriprakash Dhar Dwivedi , Ashok Prasad , Kuldeep Natwarlal Jain , Kumar Kamlesh Singh , Jitendra Maganbhai Gajera
IPC分类号： C07D473/04
CPC分类号： C07D473/04 , C07D473/06 , Y10T428/2982
摘要： The present invention relates to an amorphous form of linagliptin and processes for the preparation thereof. The invention also relates to a pharmaceutical composition comprising therapeutically effective amount of an amorphous form of linagliptin and use of said composition for treatment of diabetes especially type-I or type-II, prediabetes or reduction of glucose tolerance.
摘要翻译： 本发明涉及无定形形式的利格列汀及其制备方法。 本发明还涉及药物组合物，其包含治疗有效量的无定形形式的利格列汀，并且所述组合物用于治疗糖尿病尤其是I型或II型，糖尿病前期或葡萄糖耐量降低的用途。
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公开(公告)号：US12065414B2
公开(公告)日：2024-08-20
申请号：US17465197
申请日：2021-09-02
发明人： Kumar Kamlesh Singh , Sanjay Jagdish Desai , Kuldeep Natwarlal Jain , Jitesh Amratlal Desai , Sarvil Dhirajbhai Patel
IPC分类号： C07D261/04
CPC分类号： C07D261/04
摘要： The invention relates to process for the preparation of isoxazoline-substituted benzamide compound and intermediates thereof. The invention also relates to process for the preparation of Fluralaner and intermediates thereof.
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公开(公告)号：US10815227B2
公开(公告)日：2020-10-27
申请号：US16548992
申请日：2019-08-23
IPC分类号： C07D417/10
摘要： The present invention relates to processes for the preparation of Filgotinib. The present invention relates to novel processes for the preparation of filgotinib. The present invention also relates to novel intermediates for the preparation of filgotinib.
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公开(公告)号：US09879011B2
公开(公告)日：2018-01-30
申请号：US14384567
申请日：2013-03-12
发明人： Shriprakash Dhar Dwivedi , Ashok Prasad , Kuldeep Natwarlal Jain , Kumar Kamlesh Singh , Jitendra Maganbhai Gajera
IPC分类号： C07D473/04 , C07D473/06
CPC分类号： C07D473/04 , C07D473/06 , Y10T428/2982
摘要： The present invention relates to an amorphous form of linagliptin and processes for the preparation thereof. The invention also relates to a pharmaceutical composition comprising a therapeutically effective amount of an amorphous form of linagliptin and use of the composition for treatment of diabetes especially type-I or type-II, prediabetes or reduction of glucose tolerance.
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公开(公告)号：US20160039759A1
公开(公告)日：2016-02-11
申请号：US14816861
申请日：2015-08-03
发明人： Sanjay Jagdish DESAI , Jayprakash Ajitsingh Parihar , Kuldeep Natwarlal Jain , Sachin Ashokrao Patil
IPC分类号： C07D213/64
CPC分类号： C07D213/64
摘要： The present invention relates to processes for the preparation of perampanel and its intermediates.
摘要翻译： 本发明涉及制备睫毛膏及其中间体的方法。
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