公开(公告)号：US10182986B2

公开(公告)日：2019-01-22

申请号：US15358206

申请日：2016-11-22

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Devin Wiley ,  Andrew Clark ,  Mark E. Davis

IPC: A61K9/00 ,  A61K31/4045 ,  A61K31/137 ,  A61K51/12 ,  A61K47/59 ,  A61K47/64 ,  A61K47/69

Abstract: Described herein are methods of delivering a nanoparticle across the blood brain barrier to the brain of a subject by administering to the subject a nanoparticle having a nanoparticle core and a targeting agent. A variety of targeting agents may serve to promote delivery of the described nanoparticle.