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公开(公告)号:US11545236B2
公开(公告)日:2023-01-03
申请号:US15444247
申请日:2017-02-27
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor: Shyam M. Saladi , William M. Clemons
Abstract: Membrane protein expression can be predicted using statistical frameworks to provide an enhanced subset of sequences, out of an initial larger set of potentially expressing sequences, by using features derived from sequences and a model parameterized through a dataset of known expression levels. Also, membrane protein experimentation protocols can be designed using the statistical frameworks in concert known outcomes to identify which laboratory conditions are most likely to produce successful results.