公开(公告)号：US20240009483A1

公开(公告)日：2024-01-11

申请号：US18011323

申请日：2021-06-28

Applicant: CANCER RESEARCH TECHNOLOGY LIMITED

Inventor： Frank van den Heuvel

IPC: A61N5/10 ,  G16H20/40

CPC classification number: A61N5/103 ,  A61N5/1064 ,  G16H20/40

Abstract: We describe a method and a computer system for analysing a radiation treatment plan using a dose of flash radiation to irradiate a volume within a patient and a radiation treatment system using the same. The computer system comprises a processor which is configured to obtain oxygen pressure information for the volume to be irradiated; obtain parameters from a patient treatment plan; input the obtained oxygen pressure information and parameters in to a model which predicts complex damage within the irradiated volume caused by the dose of flash radiation; output a prediction, using the model, of the complex damage caused within the volume by the dose of flash radiation; and quantify, using the prediction, a level of damage to healthy tissue within the irradiated volume. Complex damage is damage which is more complex than a double strand break within DNA in patient tissue and the model is a function of energy of particles within the radiation and oxygen pressure which varies with time.