公开(公告)号：US20200179333A1

公开(公告)日：2020-06-11

申请号：US16793861

申请日：2020-02-18

申请人： CASE WESTERN RESERVE UNIVERSITY

发明人： Alagramam N. Kumar ,  Suhasini Gopal Ramanujam

IPC分类号： A61K31/357 ,  A61K31/343 ,  A61P27/16

摘要： A method of treating a glycosylation-defective protein associated disease or disorder in a subject, the method includes administering to the subject a therapeutically effective amount of a Sarco/ER ATPase (SERCA) inhibitor.

公开(公告)号：US20220168269A1

公开(公告)日：2022-06-02

申请号：US17468274

申请日：2021-09-07

申请人： CASE WESTERN RESERVE UNIVERSITY

发明人： Alagramam N. Kumar ,  Suhasini Gopal Ramanujam

IPC分类号： A61K31/357 ,  A61P27/16 ,  A61K31/343

摘要： A method of treating a glycosylation-defective protein associated disease or disorder in a subject, the method includes administering to the subject a therapeutically effective amount of a Sarco/ER ATPase (SERCA) inhibitor.

公开(公告)号：US11865103B2

公开(公告)日：2024-01-09

申请号：US17468274

申请日：2021-09-07

申请人： CASE WESTERN RESERVE UNIVERSITY

发明人： Alagramam N. Kumar ,  Suhasini Gopal Ramanujam

IPC分类号： A61K31/12 ,  A61K31/34 ,  A61K31/335 ,  A61K31/435 ,  A61K33/00 ,  A61K31/357 ,  A61P27/16 ,  A61K31/343

CPC分类号： A61K31/357 ,  A61K31/343 ,  A61P27/16

摘要： A method of treating a glycosylation-defective protein associated disease or disorder in a subject, the method includes administering to the subject a therapeutically effective amount of a Sarco/ER ATPase (SERCA) inhibitor.

公开(公告)号：US11110076B2

公开(公告)日：2021-09-07

申请号：US16793861

申请日：2020-02-18

申请人： CASE WESTERN RESERVE UNIVERSITY

发明人： Alagramam N. Kumar ,  Suhasini Gopal Ramanujam

IPC分类号： A61K31/12 ,  A61K31/34 ,  A61K31/335 ,  A61K31/435 ,  A61K33/00 ,  A61K31/357 ,  A61P27/16 ,  A61K31/343

摘要： A method of treating a glycosylation-defective protein associated disease or disorder in a subject, the method includes administering to the subject a therapeutically effective amount of a Sarco/ER ATPase (SERCA) inhibitor.