公开(公告)号：US20170166637A1

公开(公告)日：2017-06-15

申请号：US15039022

申请日：2014-11-25

Applicant: CCAM BIOTHERAPEUTICS LTD.

Inventor： Tehila BEN-MOSHE ,  Yair SAPIR ,  Ilana MANDEL ,  Edna MEILIN

IPC: C07K16/28 ,  A61K39/395 ,  A61K35/17

CPC classification number: C07K16/2803 ,  A61K35/17 ,  A61K39/39558 ,  A61K2035/124 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/2818 ,  C07K16/2827 ,  C07K2317/33 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/92

Abstract: The present invention provides compositions comprising anti-CEACAM1 antibodies, compositions comprising antibodies capable of inhibiting or blocking the interaction between PD-1 and its ligands, and methods for their combined use in treating cancer.