公开(公告)号：US20230248776A1

公开(公告)日：2023-08-10

申请号：US17918093

申请日：2021-10-08

Applicant: CEFO Co., Ltd.

Inventor： Hyun Sook PARK ,  Yeon Kyung LEE ,  Eun Jin GO ,  Ha Jin KIM ,  Sun Ray LEE ,  Ah Reum KWON

IPC: A61K35/32 ,  A61P19/08

CPC classification number: A61K35/32 ,  A61P19/08

Abstract: The present invention relates to a method for differentiating mesenchymal stem cells into osteoblasts, a cell therapeutic agent for treating bone disease including osteoblasts differentiated by the method and a method for producing the same. In addition, the present invention relates to a method for treating bone disease, including the step of administering the osteoblasts obtained by the method to a patient with bone disease.
The differentiation method according to the present invention can stably and rapidly differentiate mesenchymal stem cells into osteoblasts. The differentiated osteoblasts have excellent blood vessel-forming ability and excellent bone-forming ability. Accordingly, the method for differentiating stem cells into osteoblasts and the osteoblasts obtained by the method, according to the present invention, can be effectively used as a cell therapeutic agent or treatment method related to bone disease.