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公开(公告)号:US20230384312A1
公开(公告)日:2023-11-30
申请号:US18249830
申请日:2021-10-22
申请人: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS , UNIVERSITE D'ANGERS , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
IPC分类号: G01N33/574
CPC分类号: G01N33/57438 , G01N33/57484 , G01N2333/988
摘要: A method of predicting the risk of recurrence in a subject undergoing treatment for, or having undergone treatment for, clear cell renal cell carcinoma (ccRCC), by comparing the level of extracellular vesicles, preferably microvesicles, expressing carbonic anhydrase 9 (CA9+ MVs) in a sample from the subject with a reference level. Also, a method of diagnosing ccRCC or identifying a risk of developing ccRCC, by comparing the level of CA9+ MVs in a sample from the subject with a reference level.