公开(公告)号：US10047073B2

公开(公告)日：2018-08-14

申请号：US15148884

申请日：2016-05-06

Applicant: CHDI Foundation, Inc.

Inventor： Michel C. Maillard ,  Perla Breccia ,  Celia Dominguez ,  Alan F. Haughan ,  Rebecca E. Jarvis ,  Christopher A. Luckhurst ,  Elizabeth A. Saville-Stones ,  Andrew J. Stott ,  Amanda Van de Poël ,  Michael Wall ,  Grant Wishart

IPC: C07D413/12 ,  C07D491/107

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.

公开(公告)号：US20160333001A1

公开(公告)日：2016-11-17

申请号：US15148884

申请日：2016-05-06

Applicant: CHDI Foundation, Inc.

Inventor： Celia Dominguez ,  Michel C. Maillard ,  Perla Breccia ,  Alan F. Haughan ,  Rebecca E. Jarvis ,  Christopher A. Luckhurst ,  Elizabeth A. Saville-Stones ,  Andrew J. Stott ,  Amanda Van de Poël ,  Michael Wall ,  Grant Wishart

IPC: C07D413/12 ,  C07D491/107

CPC classification number: C07D413/12 ,  C07D491/107

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.

公开(公告)号：US20190185463A1

公开(公告)日：2019-06-20

申请号：US16046268

申请日：2018-07-26

Applicant: CHDI Foundation, Inc.

Inventor： Michel C. Maillard ,  Perla Breccia ,  Celia Dominguez ,  Alan F. Haughan ,  Rebecca E. Jarvis ,  Christopher A. Luckhurst ,  Elizabeth A. Saville-Stones ,  Andrew J. Stott ,  Amanda Van de Poël ,  Michael Wall ,  Grant Wishart

IPC: C07D413/12 ,  C07D491/107

CPC classification number: C07D413/12 ,  C07D491/107

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.

公开(公告)号：US10053434B2

公开(公告)日：2018-08-21

申请号：US15148907

申请日：2016-05-06

Applicant: CHDI Foundation, Inc.

Inventor： Michel C. Maillard ,  Perla Breccia ,  Celia Dominguez ,  Alan F. Haughan ,  Amanda Van de Poël ,  Andrew J. Stott ,  Christopher A. Luckhurst ,  Elizabeth A. Saville-Stones ,  Grant Wishart ,  Michael Wall ,  Rebecca E. Jarvis

IPC: C07D413/12 ,  C07D271/06 ,  C07D471/04

CPC classification number: C07D271/06 ,  C07D413/12 ,  C07D471/04

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.

公开(公告)号：US20220388998A1

公开(公告)日：2022-12-08

申请号：US17621567

申请日：2020-06-26

Applicant: CHDI Foundation, Inc

Inventor： Michel C. Maillard ,  Matthew R. Lee ,  Celia Dominguez ,  Michael Barnes ,  Alan F. Haughan ,  Tammy Ladduwahetty ,  Christopher A. Luckhurst ,  Andrew J. Stott ,  Jason Tierney

IPC: C07D413/14 ,  C07D401/04 ,  C07D405/14 ,  C07D471/04 ,  C07D213/75 ,  C07D487/04 ,  C07D487/08

Abstract: Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease in particular.

公开(公告)号：US20190202795A1

公开(公告)日：2019-07-04

申请号：US16046254

申请日：2018-07-26

Applicant: CHDI Foundation, Inc.

Inventor： Michel C. Maillard ,  Perla Breccia ,  Celia Dominguez ,  Alan F. Haughan ,  Amanda Van de Poël ,  Andrew J. Stott ,  Christopher A. Luckhurst ,  Elizabeth A. Saville-Stones ,  Grant Wishart ,  Michael Wall ,  Rebecca E. Jarvis

IPC: C07D271/06 ,  C07D413/12 ,  C07D471/04

CPC classification number: C07D271/06 ,  C07D413/12 ,  C07D471/04

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.

公开(公告)号：US20160326124A1

公开(公告)日：2016-11-10

申请号：US15148907

申请日：2016-05-06

Applicant: CHDI Foundation, Inc.

Inventor： Celia Dominguez ,  Michel C. Maillard ,  Alan F. Haughan ,  Amanda Van de Poël ,  Andrew J. Stott ,  Christopher A. Luckhurst ,  Elizabeth A. Saville-Stones ,  Grant Wishart ,  Michael Wall ,  Perla Breccia ,  Rebecca E. Jarvis

IPC: C07D271/06 ,  C07D471/04 ,  C07D413/12

CPC classification number: C07D271/06 ,  C07D413/12 ,  C07D471/04

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.