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公开(公告)号：US20230193292A1
公开(公告)日：2023-06-22
申请号：US18020578
申请日：2021-08-16
发明人： Zipeng ZHEN , Meijuan XIE , Xiuzhen DU , Yimin MA , Bing ZHANG , Tongjie XU , Xiquan ZHANG
摘要： A BCMA-binding immunoglobulin single variable structural domain and an antigen-binding molecule including an immunoglobulin single variable structural domain and an antigen-binding molecule, a nucleic acid encoding the above, a vector containing the nucleic acid, a cell containing the vector, and a pharmaceutical composition containing the above, as well as a therapeutic use thereof.
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公开(公告)号：US20230265181A1
公开(公告)日：2023-08-24
申请号：US18020584
申请日：2021-08-16
发明人： Zipeng ZHEN , Meijuan XIE , Xiuzhen DU , Yimin MA , Bing ZHANG , Tongjie XU , Xiquan ZHANG
CPC分类号： C07K16/241 , A61P35/00 , C07K2317/565 , C07K2317/24 , C07K2317/22 , C07K2317/52
摘要： An immunoglobulin single variable domain and antigen binding molecule binding BCMA, specifically comprising an immunoglobulin single variable domain and antigen binding molecule, a nucleic acid for encoding the binding molecule, a vector containing the nucleic acid, a cell containing the vector, and a pharmaceutical composition containing the above.
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公开(公告)号：US20240182592A1
公开(公告)日：2024-06-06
申请号：US18285511
申请日：2022-04-14
发明人： Bing ZHANG , Wei ZHAO , Yamin LU , Min DU , Zipeng ZHEN , Meijuan XIE , Xin WANG , Junxiao XI , Xin SONG , Xiuzhen DU
IPC分类号： C07K16/28
CPC分类号： C07K16/2878 , C07K16/2809 , C07K2317/31 , C07K2317/569
摘要： A multi-specific antibody targeting BCMA. Specifically provided are a multi-specific antibody, a nucleic acid encoding same, a vector including the nucleic acid, a cell including the vector, and a pharmaceutical composition including same. Further provided is the use thereof for treating a subject having a disease related to BCMA expression.
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