公开(公告)号：US11891398B2

公开(公告)日：2024-02-06

申请号：US17058308

申请日：2019-05-24

申请人： CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

发明人： Haiying He ,  Jianhua Xia ,  Zhen Gong ,  Jian Li ,  Shuhui Chen

IPC分类号： C07D487/04 ,  A61P31/20

CPC分类号： C07D487/04 ,  A61P31/20

摘要： The present application relates to a 2,3-dihydro-1H-pyrrolizine-7-formamide derivative as a nucleoprotein inhibitor and a use in preparation of a drug for treating HBV related diseases. The present application specifically relates to a compound represented by formula (II), and isomers or pharmaceutically acceptable salts thereof.

公开(公告)号：US11014943B2

公开(公告)日：2021-05-25

申请号：US16489282

申请日：2018-02-28

申请人： CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

发明人： Jian Xiong ,  Cheng Xie ,  Kevin X Chen ,  Xiongbin Xu ,  Xuejin Zhang ,  Zhen Gong ,  Jian Li ,  Shuhui Chen ,  Aiming Zhang ,  Zhulian Jiang ,  Xiquan Zhang ,  Xin Tian

IPC分类号： C07F5/02 ,  A61P35/00

摘要： Disclosed in the present application are a compound represented by formula (I), or a pharmaceutically acceptable salt, a tautomer thereof, a stereoisomer thereof, or a geometrical isomer thereof, and uses thereof in the preparation of drugs for treating or preventing multiple myeloma.