专利检索 ap:("CHIMERIX, INC.") AND inv:"Richard S. POTTORF" 第 1 页

1.

发明公开
7-BENZYL-4-(2-METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZ0[1,2-A]PYRID0[3,4-E] PYRIMIDIN-5 (1 H)-ONE, ANALOGS THEREOF, AND SALTS THEREOF AND METHODS FOR THEIR USE IN THERAPY 审中-公开

公开(公告)号：US20240270746A1

公开(公告)日：2024-08-15

申请号：US18603075

申请日：2024-03-12

申请人： CHIMERIX, INC.

发明人： Joshua E. Allen , Martin STOGNIEW , Richard S. POTTORF , Bhaskara Rao NALLAGANCHU , Gary OLSON , Yanjun SUN

IPC分类号： C07D471/14 , A61K31/337 , A61K31/519 , A61K45/06 , C07D471/12 , C07D487/14

CPC分类号： C07D471/14 , A61K31/337 , A61K31/519 , A61K45/06 , C07D471/12 , C07D487/14 , Y02A50/30

摘要： This disclosure relates to methods of treatment using compound (1) or analogs thereof, and pharmaceutically acceptable salts thereof. Also disclosed are compounds of formula (10):

as defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the same. Methods of treatment, such as for cancer, are provided that comprise administering the compounds and their salts to a subject in need of such treatment.

2.

发明申请
7-BENZYL-4-(2-METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZO [1,2-a]PYRIDO[3,4-e]PYRIMIDIN-5(1H)-ONE, ANALOGS THEREOF, AND SALTS THEREOF AND METHODS FOR THEIR USE IN THERAPY 有权

公开(公告)号：US20220017519A1

公开(公告)日：2022-01-20

申请号：US17357008

申请日：2021-06-24

申请人： CHIMERIX, INC.

发明人： Joshua E. ALLEN , Martin STOGNIEW , Richard S. POTTORF , Bhaskara Rao NALLAGANCHU , Gary OLSON , Yanjun SUN

IPC分类号： C07D471/14 , A61K31/519 , C07D471/12 , C07D487/14 , A61K45/06 , A61K31/337

摘要： This disclosure relates to methods of treatment using compound (1) or analogs thereof, and pharmaceutically acceptable salts thereof. Also disclosed are compounds of formula (10): as defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the same. Methods of treatment, such as for cancer, are provided that comprise administering the compounds and their salts to a subject in need of such treatment.