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公开(公告)号：US20150166480A1
公开(公告)日：2015-06-18
申请号：US14407214
申请日：2013-06-11
发明人： ChangSik Lee , TaegSu Jang , DaeKyu Choi , MooSung Ko , DoHoon Kim , SoYoung Kim , JaeKi Min , WooSik Kim , YoungTae Lim
IPC分类号： C07D211/22 , C07D401/14 , C07D405/12 , C07D401/12 , C07D409/12
CPC分类号： C07D211/22 , A61K31/454 , A61K31/4545 , A61K31/4985 , C07D211/42 , C07D211/60 , C07D211/62 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D487/04 , A61K2300/00
摘要： The present invention relates to novel piperidine derivatives, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compound; and pharmaceutical compositions comprising the compound. The novel piperidine derivatives, according to the present invention, having an effect as GPR119 agonist can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders.
摘要翻译： 本发明涉及新的哌啶衍生物，其立体异构体或其药学上可接受的盐; 制备化合物的方法; 和包含该化合物的药物组合物。 根据本发明的具有GPR119激动剂作用的新型哌啶衍生物可用于治疗代谢紊乱，包括糖尿病（特别是II型）和相关疾病。
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公开(公告)号：US09776987B2
公开(公告)日：2017-10-03
申请号：US15039226
申请日：2014-11-25
发明人： Yuntae Kim , ChangSik Lee , DaeKyu Choi , MooSung Ko , Younghue Han , SoYoung Kim , JaeKi Min , DoHoon Kim
IPC分类号： C07D401/12 , C07D401/14
CPC分类号： C07D401/12 , C07D401/14
摘要： The present invention relates to novel amide derivatives, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compound; and pharmaceutical compositions comprising the compound. The novel amide derivatives, according to the present invention, having an effect as GPR119 agonist can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders.
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公开(公告)号：US09944600B2
公开(公告)日：2018-04-17
申请号：US14407214
申请日：2013-06-11
发明人： ChangSik Lee , TaegSu Jang , DaeKyu Choi , MooSung Ko , DoHoon Kim , SoYoung Kim , JaeKi Min , WooSik Kim , YoungTae Lim
IPC分类号： C07D211/22 , C07D401/14 , C07D401/12 , C07D409/12 , C07D487/04 , C07D211/42 , C07D211/60 , C07D211/62 , A61K31/454 , A61K31/4545 , A61K31/4985 , C07D405/12
CPC分类号： C07D211/22 , A61K31/454 , A61K31/4545 , A61K31/4985 , C07D211/42 , C07D211/60 , C07D211/62 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D487/04 , A61K2300/00
摘要： The present invention relates to novel piperidine derivatives, stereoisomers thereof or pharmaceutically acceptable salts thereof; methods for preparing the compound; and pharmaceutical compositions comprising the compound. The novel piperidine derivatives, according to the present invention, having an effect as GPR119 agonist can be used for treatment of metabolic disorders, including diabetes mellitus (especially type II) and related disorders.
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