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公开(公告)号:US20100280227A1
公开(公告)日:2010-11-04
申请号:US12835570
申请日:2010-07-13
申请人: CHRISTINE M. AMBROSE , MERCEDESZ BALAZS , LAURA DEFORGE , MARK S. DENNIS , GERMAINE FUH , STEPHEN D. HURST , CHINGWEI V. LEE , HENRY B. LOWMAN , FLAVIUS MARTIN , GERALD R. NAKAMURA , DHAYA SESHASAYEE , MELISSA A. STAROVASNIK , JEFFREY S. THOMPSON
发明人: CHRISTINE M. AMBROSE , MERCEDESZ BALAZS , LAURA DEFORGE , MARK S. DENNIS , GERMAINE FUH , STEPHEN D. HURST , CHINGWEI V. LEE , HENRY B. LOWMAN , FLAVIUS MARTIN , GERALD R. NAKAMURA , DHAYA SESHASAYEE , MELISSA A. STAROVASNIK , JEFFREY S. THOMPSON
IPC分类号: C07K16/18
CPC分类号: C07K16/2878 , C07K2317/34 , C07K2317/732
摘要: The present invention relates to novel BR3 binding antibodies and polypeptides, including antagonist and agonist polypeptides. The present invention also relates to the use of the BR3 binding antibodies and polypeptides in, e.g., methods of treatment, screening methods, diagnostic methods, assays and protein purification methods.
摘要翻译: 本发明涉及新型BR3结合抗体和多肽,包括拮抗剂和激动剂多肽。 本发明还涉及例如治疗方法,筛选方法,诊断方法,测定和蛋白质纯化方法中BR3结合抗体和多肽的用途。