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公开(公告)号：US20180142067A1
公开(公告)日：2018-05-24
申请号：US15587064
申请日：2017-05-04
Applicant: COMSATS Institute of Information Technology
Inventor： Muhammad Yar , Lubna Shahzadi
CPC classification number: C08G81/00 , A01N43/16 , A61L15/28 , A61L15/425 , A61L15/44 , A61L26/0023 , A61L26/0066 , A61L2400/06
Abstract: A water soluble biocompatible hydrogel having an amino sugar linked to a hydrophilic polymer is disclosed. Linkage of the amino sugar and hydrophilic polymer may be provided by an imine-amine bond between an amine of the amino sugar and a primary amine of the hydrophilic polymer. The linkage between the amino sugar and the hydrophilic polymer may be provided by reacting an amine of the amino sugar and a primary amine of the hydrophilic polymer with a formate ester in an acidic solution. Water soluble biocompatible polymer having an amino sugar linked to a hydrophilic polymer may be cast into films, dried into gauze and/or combined with salt solutions to provide injectable gels.
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公开(公告)号：US10059809B2
公开(公告)日：2018-08-28
申请号：US15587064
申请日：2017-05-04
Applicant: COMSATS Institute of Information Technology
Inventor： Muhammad Yar , Lubna Shahzadi
Abstract: A water soluble biocompatible hydrogel having an amino sugar linked to a hydrophilic polymer is disclosed. Linkage of the amino sugar and hydrophilic polymer may be provided by an imine-amine bond between an amine of the amino sugar and a primary amine of the hydrophilic polymer. The linkage between the amino sugar and the hydrophilic polymer may be provided by reacting an amine of the amino sugar and a primary amine of the hydrophilic polymer with a formate ester in an acidic solution. Water soluble biocompatible polymer having an amino sugar linked to a hydrophilic polymer may be cast into films, dried into gauze and/or combined with salt solutions to provide injectable gels.
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