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公开(公告)号:US20190076439A1
公开(公告)日:2019-03-14
申请号:US15762533
申请日:2016-09-19
发明人: Ana MARTÍNEZ GIL , Carmen GIL AYUSO-GONTAN , Nuria CAMPILLO MARTÍN , Maria José SANCHEZ BARRENA , Alicia MANSILLA APARICIO , Alberto FERRÚS GAMERO
IPC分类号: A61K31/5415 , A61P25/00
摘要: The present invention relates to the use of a group of compounds with a phenothiazine core with the following general formula (I): for treating diseases of the central nervous system which present abnormalities in the synapse such as autism or Fragile X syndrome. The compounds of the invention are involved in the interaction of the NCS1 and Ric8 proteins involved in the synaptogenesis process.