公开(公告)号：US20250073138A1

公开(公告)日：2025-03-06

申请号：US18778212

申请日：2024-07-19

Applicant: COSMECCA KOREA CO., LTD. ,  Research & Business Foundation SUNGKYUNKWAN UNIVERSITY

Inventor： Ji Soo Ryu ,  Jae Yong Seo ,  Hang Eui Cho ,  Hyun Dae Cho ,  Jin Woong Kim ,  Minha Jeon ,  Seulgi Kim ,  Se Eun Kim

IPC: A61K8/14 ,  B82Y5/00

Abstract: The present invention relates to a lipid-based nanoparticle composition for enhancing transdermal absorption and a method of preparing the same. The present invention provides a carrier for enhancing transdermal absorption that enhances or promotes chemical bonding with skin tissue by modifying the surface of lipid nanoparticles with a polyphenol. This may demonstrate the synergistic effect of active and passive transdermal delivery systems.

公开(公告)号：US20250057767A1

公开(公告)日：2025-02-20

申请号：US18807111

申请日：2024-08-16

Applicant: COSMECCA KOREA CO., LTD. ,  GFC Life Science Co., Ltd. ,  KOREA BASIC SCIENCE INSTITUTE

Inventor： Ji Soo Ryu ,  A Reum Jang ,  Jae Yong Seo ,  Hyun Dae Cho ,  Hee Cheol Kang ,  Mi Jung Kim ,  En Young Jeong ,  Hye Sun Park ,  Kwan Soo Hong ,  Hyunseung Lee

IPC: A61K9/127 ,  A61K8/14 ,  A61K8/9789 ,  A61K9/50

Abstract: The present invention relates to hybrid exosomes, a use of the same, and a preparation method of the same, and the hybrid exosomes provided from the present invention have excellent skin inflammation amelioration, skin wrinkle amelioration, skin moisturization efficacy, and skin regeneration efficacy compared to using hydrangea-derived exosomes and liposomes alone, and thus can be effectively utilized as a cosmetic composition containing the same as an active ingredient. In addition, the hybrid exosomes have better stability and biocompatibility compared to existing exosomes.

公开(公告)号：US11213464B2

公开(公告)日：2022-01-04

申请号：US16496477

申请日：2019-03-12

Applicant: COSMECCA KOREA Co., Ltd.

Inventor： Hyun Dae Cho ,  Jae Yong Seo ,  Ju Tae Jeong ,  Soon Ho Choi ,  Jung Won Shin

IPC: A61K8/06 ,  A61K8/04 ,  A61K8/34 ,  A61K8/36 ,  A61K8/60 ,  A61K8/73 ,  A61K8/81 ,  A61K8/86 ,  A61K8/89 ,  A61K8/92 ,  A61Q1/02 ,  A61K8/891

Abstract: A solid temporal colorimetric hydrogel cosmetic composition includes 15 to 99.90 wt % of the water phase part and 0.10 to 85 wt % of the oil phase part, having a refractive index difference of 0 to 0.02 therebetween, and having a color change according to variations in a refractive index difference between the water phase part and the oil phase difference when applied to the skin. The cosmetic composition not only has flexibility through irradiation of gamma-rays, but also enables an optimal application time of the cosmetic composition to be visually confirmed through a color change from transparency to ivory white due to a change in the refractive index difference caused by absorbency and volatilization of water when applying the composition to the skin. The cosmetic composition is capable of improving quality of a product although a preservative irritating to the skin is not added.