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公开(公告)号：US09890132B2
公开(公告)日：2018-02-13
申请号：US14914378
申请日：2014-08-25
Inventor： Chepuri Venkata Ramana , Yadagiri Kommagalla , Kolluru Srinivas
IPC: C07D307/80
CPC classification number: C07D307/80
Abstract: Disclosed herein an efficient process for synthesis of benzofuran analogs having anti-inflammatory activity which comprises, Ru-catalyzed branched and linear selective alkylation of aroylbenzofurans formula-I with alpha, beta unsaturated esters of formula-II via C—H activation in presence of base, additives and organic solvent at suitable temperature to give high yield of desired linear alkylated benzofuran compounds of formula-III or branched alkylated benzofuran compounds of formula-IV or mixture thereof.
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